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PHYSICIAN-LED CONTRACT RESEARCH

You bring the question. We build the evidence

If you're stuck on your research project, you're in the right place to move it forward.

Study AStudy BStudy CStudy DStudy E0.250.5124PooledWeight20.7%18.8%18.0%12.3%30.2%
Pooled
1.33
95% CI
1.16–1.52
Heterogeneity
I² = 1%
Significance
p < 0.001
Illustrative figure — drag any point estimate to see the pooled result recalculate.

Method before output

A better statistical test will not save a badly framed question.

Most research support ends at the deliverable: a table, a plot, a draft, handed over without the thinking that produced it. That works until someone asks why you chose that comparator, or that model, or that cutoff. Then the deliverable is worth nothing and you are on your own. We work the other way round.

  1. 01

    The methodology is clinical, not just statistical

    Choosing an outcome, a comparator or an eligible population is a medical judgement before it is a technical one. A statistician can run the wrong analysis flawlessly. A clinician can pick the right outcome and analyse it badly. We work at the point where those two failures meet.

  2. 02

    Every analysis arrives with its code

    You receive the documented R or Stata script alongside the results. Re-run it, extend it, hand it to a reviewer, or check it against your own understanding. A number you cannot trace is a number you cannot defend.

  3. 03

    We write down what the evidence does not show

    Limitations are stated plainly and proportionately, not buried in a closing paragraph. A study with honest limits survives peer review. A study with hidden ones gets found out, usually in public.

Read the method yourself

Our published research is the sample of our work.

We are a new company. We are not new to the method. The evidence syntheses below were co-authored by our team and carry a DOI each. Read the search strategy. Read the risk-of-bias assessment. Read how the limitations are worded. That is the standard your project gets.

  1. Genidy AM, Awad A, Abdelsalam OK, Hamed BM, Ibrahim NM, Khaled AKM, et al. Robot-assisted endoscopic submucosal dissection in gastrointestinal lesions: a systematic review and meta-analysis. Clin Res Hepatol Gastroenterol. 2026;50(2):102752. doi:10.1016/j.clinre.2025.102752

    Read the record →
  2. Mady A, Kashbour M, Abu-Qaree O, Jaffal R, Khaled A, Daoud A, et al. Rheumatoid arthritis drugs and the risk of Parkinson disease: a meta-analysis. NeuroImmune Pharmacol Ther. 2025;4(1):13-26. doi:10.1515/nipt-2024-0023

    Read the record →
  3. Mahmoud MAT, Hamam NG, Ghanm TIE, Khaled A, Osman ASA, Beddor A, et al. Comparing distal and proximal radial access for percutaneous coronary intervention and angiography: a comprehensive meta-analysis and systematic review of randomized controlled trials. Coron Artery Dis. 2025;36(6):e1-e11. doi:10.1097/MCA.0000000000001489

    Read the record →

What we take on

Every stage, from the first question to the reviewer’s last comment.

Bring the whole study, or the one part that has stalled. Both are normal, and neither is treated as the lesser request.

01

Evidence synthesis

Turn a scattered literature into one pooled answer you can defend line by line.

PRISMA screening flowRecords narrowing through four stages: identification, screening, eligibility, and the studies finally included.
PRISMA screening flow
  • Systematic reviews
  • Meta-analysis
  • Evidence synthesis

3 services

Explore Evidence synthesis

  1. Biostatistics

    Hand over the dataset and get back the analysis, the figures, and the code to re-run it.

    • Biostatistics
    • Statistical analysis

    2 services

  2. Real-world data

    Answer your question with data that already exists, instead of spending two years collecting it.

    • Real-world data

    1 service

  3. Study design

    Fix the design flaw now, while it is still a conversation and not an unfixable study.

    • Study design
    • Research protocols

    2 services

  4. Publication support

    Get the manuscript out of the drawer, through review, and into a journal that fits it.

    • Manuscript and publication support
    • Reviewer response

    2 services

The working relationship

You review the decisions while they can still be changed.

Work arrives in milestones, so you see the methodology before it is baked into six months of analysis.

  1. 01

    Scope

    Tell us what you are trying to find out. We assess whether the question can be answered with the evidence or data available, and if it cannot, that is what you hear before you commission anything.

  2. 02

    Method, agreed in writing

    We specify the design, the outcomes, the analysis plan and the reporting standard the work will be held to. You approve it before anything is run.

  3. 03

    Delivery, in stages

    Protocol, then search, then analysis, then draft. You review each stage. Nothing arrives as a finished object you have to accept or reject whole.

  4. 04

    Revision, including after submission

    We refine on your feedback and, where the scope includes it, stay with the manuscript through peer review and write the response with you.

Two ways to work with us

One study, or one stalled stage.

You do not have to hand over the whole project to get help with the part that is not moving.

  • Complete research workflow

    From an idea to a manuscript on a journal’s desk

    One team carries the question through design, protocol, analysis, interpretation, writing and revision. Nothing is handed between vendors, so nothing is lost in the handover. Best when the study has not started, or has started badly.

    • Question, design, protocol, registration
    • Analysis and interpretation
    • Manuscript, submission, reviewer response

    Scope a full project

  • A single research stage

    The specific thing you are stuck on

    A meta-analysis on data you have already extracted. A statistical analysis on a dataset you already hold. A protocol due next week. A reviewer comment you do not know how to answer.

    • Statistics on an existing dataset
    • Meta-analysis of extracted data
    • Methods, results, or a response letter

    See individual deliverables

Methods notes

One note at a time, on something that goes wrong in real studies.

Written for people running research, not for people buying services. Why a non-significant Cochran’s Q does not license a fixed-effect model. How immortal time bias gets built into a cohort definition without anyone noticing. No promotional mail, and one click to leave.

We will not sell you a publication.

Reviewers, editors, journal priorities and whether your study contributes anything new are outside our control, and outside everyone else’s. Any service that guarantees acceptance is either misdescribing peer review or describing something you would not want your name attached to. What is inside our control is the method, the transparency of the analysis, the accuracy of the reporting, and conclusions that stop where the evidence stops. Tell us what you want to find out and where you have got to. We will tell you what we think is feasible, and we will tell you if the answer is nothing.